[Download] "Progress in the Chemistry of Organic Natural Products 115" by A. Douglas Kinghorn, Heinz Falk, Simon Gibbons, Yoshinori Asakawa, Ji-Kai Liu & Verena M. Dirsch ~ Book PDF Kindle ePub Free
eBook details
- Title: Progress in the Chemistry of Organic Natural Products 115
- Author : A. Douglas Kinghorn, Heinz Falk, Simon Gibbons, Yoshinori Asakawa, Ji-Kai Liu & Verena M. Dirsch
- Release Date : January 02, 2021
- Genre: Chemistry,Books,Science & Nature,Professional & Technical,Medical,Life Sciences,
- Pages : * pages
- Size : 29400 KB
Description
This book describes current understandings and recent progress into a varied group of natural products. In the first chapter the role that total synthesis may play in revising the structures proposed for decanolides, which are ten-membered lactones found primarily in fungi, frogs, and termites is presented. The following chapter presents the development of the intriguing plant-derived sesquiterpene lactone, thapsigargin, a potent inhibitor of the enzyme, SERCA (sarco-endoplasmic Ca2+ ATPase), which has potential as a lead compound to treat cancer. The third chapter covers the potential of various plant phenolic compounds for treating the tropical and sub-tropical infectious disease, leishmaniasis. In addition the volume presents recent advances related to the plant alkaloid, cryptolepine, which is of particular interest as a lead for the treatment of malaria, trypanosomiasis, and cancer.